| Acrylamide | TT⁴ | Nervous system or blood problems; increased risk of cancer | Added to water during sewage/wastewater treatment | zero |
| Alachlor | 0.002 | Eye, liver, kidney, or spleen problems; anemia; increased risk of cancer | Runoff from herbicide used on row crops | zero |
| Alpha/photon emitters | 15 pCi/L | Increased risk of cancer | Erosion of natural deposits of certain radioactive minerals that may emit alpha radiation | zero |
| Antimony | 0.006 | Increase in blood cholesterol; decrease in blood sugar | Discharge from petroleum refineries; fire retardants; ceramics; electronics; solder | 0.006 |
| Arsenic | 0.010 | Skin damage or circulatory-system problems; increased risk of cancer | Erosion of natural deposits; runoff from orchards; runoff from glass & electronics production wastes | zero |
| Asbestos (fibers >10 micrometers) | 7 MFL | Increased risk of developing benign intestinal polyps | Decay of asbestos cement in water mains; erosion of natural deposits | 7 MFL |
| Atrazine | 0.003 | Cardiovascular system or reproductive problems | Runoff from herbicide used on row crops | 0.003 |
| Barium | 2 | Increase in blood pressure | Discharge of drilling wastes; discharge from metal refineries; erosion of natural deposits | 2 |
| Benzene | 0.005 | Anemia; decrease in blood platelets; increased risk of cancer | Discharge from factories; leaching from gas storage tanks and landfills | zero |
| Benzo(a)pyrene (PAHs) | 0.0002 | Reproductive difficulties; increased risk of cancer | Leaching from linings of water storage tanks and distribution lines | zero |
| Beryllium | 0.004 | Intestinal lesions | Discharge from metal refineries and coal-burning factories; electrical, aerospace & defense industries | 0.004 |
| Beta particle & photon emitters | 4 mrem/yr | Increased risk of cancer | Decay of natural & man-made radioactive deposits emitting photon/beta radiation | zero |
| Bromate | 0.010 | Increased risk of cancer | Byproduct of drinking water disinfection | zero |
| Cadmium | 0.005 | Kidney damage | Corrosion of galvanized pipes; erosion of natural deposits; metal refineries; waste batteries & paints | 0.005 |
| Carbofuran | 0.04 | Problems with blood, nervous system, or reproductive system | Leaching of soil fumigant used on rice and alfalfa | 0.04 |
| Carbon tetrachloride | 0.005 | Liver problems; increased risk of cancer | Discharge from chemical plants and other industrial activities | zero |
| Chloramines (as Cl₂) | MRDL=4.0 | Eye/nose irritation; stomach discomfort; anemia | Water additive used to control microbes | MRDLG=4 |
| Chlordane | 0.002 | Liver or nervous system problems; increased risk of cancer | Residue of banned termiticide | zero |
| Chlorine (as Cl₂) | MRDL=4.0 | Eye/nose irritation; stomach discomfort | Water additive used to control microbes | MRDLG=4 |
| Chlorine dioxide (as ClO₂) | MRDL=0.8 | Anemia; infants, young children & fetuses of pregnant women: nervous system effects | Water additive used to control microbes | MRDLG=0.8 |
| Chlorite | 1.0 | Anemia; infants, young children & fetuses of pregnant women: nervous system effects | Byproduct of drinking water disinfection | 0.8 |
| Chlorobenzene | 0.1 | Liver or kidney problems | Discharge from chemical and agricultural chemical factories | 0.1 |
| Chromium (total) | 0.1 | Allergic dermatitis | Discharge from steel and pulp mills; erosion of natural deposits | 0.1 |
| Copper | TT⁵; AL=1.3 | Short-term: GI distress. Long-term: liver or kidney damage. Wilson's Disease patients should consult a doctor if levels exceed the action level | Corrosion of household plumbing systems; erosion of natural deposits | 1.3 |
| Cryptosporidium | TT⁷ | Short-term: gastrointestinal illness (diarrhea, vomiting, cramps) | Human and animal fecal waste | zero |
| Cyanide (as free cyanide) | 0.2 | Nerve damage or thyroid problems | Discharge from steel/metal factories; plastic and fertilizer factories | 0.2 |
| 2,4-D | 0.07 | Kidney, liver, or adrenal gland problems | Runoff from herbicide used on row crops | 0.07 |
| Dalapon | 0.2 | Minor kidney changes | Runoff from herbicide used on rights of way | 0.2 |
| 1,2-Dibromo-3-chloropropane (DBCP) | 0.0002 | Reproductive difficulties; increased risk of cancer | Runoff/leaching from soil fumigant used on soybeans, cotton, pineapples & orchards | zero |
| o-Dichlorobenzene | 0.6 | Liver, kidney, or circulatory system problems | Discharge from industrial chemical factories | 0.6 |
| p-Dichlorobenzene | 0.075 | Anemia; liver, kidney, or spleen damage; changes in blood | Discharge from industrial chemical factories | 0.075 |
| 1,2-Dichloroethane | 0.005 | Increased risk of cancer | Discharge from industrial chemical factories | zero |
| 1,1-Dichloroethylene | 0.007 | Liver problems | Discharge from industrial chemical factories | 0.007 |
| cis-1,2-Dichloroethylene | 0.07 | Liver problems | Discharge from industrial chemical factories | 0.07 |
| trans-1,2-Dichloroethylene | 0.1 | Liver problems | Discharge from industrial chemical factories | 0.1 |
| Dichloromethane | 0.005 | Liver problems; increased risk of cancer | Discharge from industrial chemical factories | zero |
| 1,2-Dichloropropane | 0.005 | Increased risk of cancer | Discharge from industrial chemical factories | zero |
| Di(2-ethylhexyl) adipate | 0.4 | Weight loss, liver problems, or possible reproductive difficulties | Discharge from chemical factories | 0.4 |
| Di(2-ethylhexyl) phthalate | 0.006 | Reproductive difficulties; liver problems; increased risk of cancer | Discharge from rubber and chemical factories | zero |
| Dinoseb | 0.007 | Reproductive difficulties | Runoff from herbicide used on soybeans and vegetables | 0.007 |
| Dioxin (2,3,7,8-TCDD) | 0.00000003 | Reproductive difficulties; increased risk of cancer | Emissions from waste incineration/combustion; discharge from chemical factories | zero |
| Diquat | 0.02 | Cataracts | Runoff from herbicide use | 0.02 |
| Endothall | 0.1 | Stomach and intestinal problems | Runoff from herbicide use | 0.1 |
| Endrin | 0.002 | Liver problems | Residue of banned insecticide | 0.002 |
| Epichlorohydrin | TT⁴ | Increased cancer risk; stomach problems | Discharge from industrial chemical factories; impurity of some water treatment chemicals | zero |
| Ethylbenzene | 0.7 | Liver or kidney problems | Discharge from petroleum refineries | 0.7 |
| Ethylene dibromide | 0.00005 | Problems with liver, stomach, reproductive system, or kidneys; increased risk of cancer | Discharge from petroleum refineries | zero |
| Fecal coliform & E. coli | MCL⁶ | Indicates possible contamination with human/animal wastes; short-term GI symptoms; special risk for infants, young children & immunocompromised | Human and animal fecal waste | zero⁶ |
| Fluoride | 4.0 | Bone disease (pain & tenderness); children may get mottled teeth | Water additive that promotes strong teeth; erosion of natural deposits; fertilizer & aluminum factories | 4.0 |
| Giardia lamblia | TT⁷ | Short-term: gastrointestinal illness (diarrhea, vomiting, cramps) | Human and animal fecal waste | zero |
| Glyphosate | 0.7 | Kidney problems; reproductive difficulties | Runoff from herbicide use | 0.7 |
| Haloacetic acids (HAA5) | 0.060 | Increased risk of cancer | Byproduct of drinking water disinfection | n/a⁹ |
| Heptachlor | 0.0004 | Liver damage; increased risk of cancer | Residue of banned termiticide | zero |
| Heptachlor epoxide | 0.0002 | Liver damage; increased risk of cancer | Breakdown of heptachlor | zero |
| Heterotrophic plate count (HPC) | TT⁷ | No health effects — an analytic method measuring bacterial variety; lower counts indicate better system maintenance | Naturally-occurring bacteria measured across the environment | n/a |
| Hexachlorobenzene | 0.001 | Liver or kidney problems; reproductive difficulties; increased risk of cancer | Discharge from metal refineries and agricultural chemical factories | zero |
| Hexachlorocyclopentadiene | 0.05 | Kidney or stomach problems | Discharge from chemical factories | 0.05 |
| Lead | TT⁵; AL=0.015 | Infants/children: developmental delays, attention & learning deficits. Adults: kidney problems, high blood pressure | Corrosion of household plumbing systems; erosion of natural deposits | zero |
| Legionella | TT⁷ | Legionnaire's Disease, a type of pneumonia | Found naturally in water; multiplies in heating systems | zero |
| Lindane | 0.0002 | Liver or kidney problems | Runoff/leaching from insecticide used on cattle, lumber & gardens | 0.0002 |
| Mercury (inorganic) | 0.002 | Kidney damage | Erosion of natural deposits; refineries & factories; runoff from landfills & croplands | 0.002 |
| Methoxychlor | 0.04 | Reproductive difficulties | Runoff/leaching from insecticide used on fruits, vegetables, alfalfa & livestock | 0.04 |
| Nitrate (as Nitrogen) | 10 | Infants <6 months: serious illness, possibly fatal (blue-baby syndrome, shortness of breath) if untreated | Runoff from fertilizer use; leaching from septic tanks, sewage; erosion of natural deposits | 10 |
| Nitrite (as Nitrogen) | 1 | Infants <6 months: serious illness, possibly fatal (blue-baby syndrome, shortness of breath) if untreated | Runoff from fertilizer use; leaching from septic tanks, sewage; erosion of natural deposits | 1 |
| Oxamyl (Vydate) | 0.2 | Slight nervous system effects | Runoff/leaching from insecticide used on apples, potatoes & tomatoes | 0.2 |
| Pentachlorophenol | 0.001 | Liver or kidney problems; increased cancer risk | Discharge from wood-preserving factories | zero |
| Picloram | 0.5 | Liver problems | Herbicide runoff | 0.5 |
| Polychlorinated biphenyls (PCBs) | 0.0005 | Skin changes; thymus gland problems; immune deficiencies; reproductive/nervous system difficulties; increased risk of cancer | Runoff from landfills; discharge of waste chemicals | zero |
| Radium 226 & 228 (combined) | 5 pCi/L | Increased risk of cancer | Erosion of natural deposits | zero |
| Selenium | 0.05 | Hair or fingernail loss; numbness in fingers or toes; circulatory problems | Discharge from petroleum & metal refineries; erosion of natural deposits; mines | 0.05 |
| Simazine | 0.004 | Problems with blood | Herbicide runoff | 0.004 |
| Styrene | 0.1 | Liver, kidney, or circulatory system problems | Discharge from rubber & plastic factories; leaching from landfills | 0.1 |
| Tetrachloroethylene | 0.005 | Liver problems; increased risk of cancer | Discharge from factories and dry cleaners | zero |
| Thallium | 0.002 | Hair loss; changes in blood; kidney, intestine, or liver problems | Leaching from ore-processing sites; electronics, glass & drug factories | 0.0005 |
| Toluene | 1 | Nervous system, kidney, or liver problems | Discharge from petroleum factories | 1 |
| Total Coliforms | 5.0 percent⁸ | Indicator that other, potentially harmful bacteria may be present (see Fecal coliform & E. coli) | Naturally present in the environment | zero |
| Total Trihalomethanes (TTHMs) | 0.080 | Liver, kidney, or central nervous system problems; increased risk of cancer | Byproduct of drinking water disinfection | n/a⁹ |
| Toxaphene | 0.003 | Kidney, liver, or thyroid problems; increased risk of cancer | Runoff/leaching from insecticide used on cotton & cattle | zero |
| 2,4,5-TP (Silvex) | 0.05 | Liver problems | Residue of banned herbicide | 0.05 |
| 1,2,4-Trichlorobenzene | 0.07 | Changes in adrenal glands | Discharge from textile finishing factories | 0.07 |
| 1,1,1-Trichloroethane | 0.2 | Liver, nervous system, or circulatory problems | Discharge from metal degreasing sites and other factories | 0.2 |
| 1,1,2-Trichloroethane | 0.005 | Liver, kidney, or immune system problems | Discharge from industrial chemical factories | 0.003 |
| Trichloroethylene | 0.005 | Liver problems; increased risk of cancer | Discharge from metal degreasing sites and other factories | zero |
| Turbidity | TT⁷ | Indicates cloudiness/filtration effectiveness; higher turbidity often correlates with higher levels of disease-causing organisms (viruses, parasites, some bacteria) | Soil runoff | n/a |
| Uranium | 30 µg/L | Increased risk of cancer, kidney toxicity | Erosion of natural deposits | zero |
| Vinyl chloride | 0.002 | Increased risk of cancer | Leaching from PVC pipes; discharge from plastic factories | zero |
| Viruses (enteric) | TT⁷ | Short-term: gastrointestinal illness (diarrhea, vomiting, cramps) | Human and animal fecal waste | zero |
| Xylenes (total) | 10 | Nervous system damage | Discharge from petroleum factories; discharge from chemical factories | 10 |